About Us
Harbour BioMed
Harbour BioMed (HKEX: 02142) is a global biopharmaceutical company committed to the discovery and development of novel antibody therapeutics in immunology, oncology and other areas. The Company is building a robust portfolio and differentiated pipeline through internal R&D capability, strategic global collaborations in co-discovery and co-development, and selective acquisitions.

Our proprietary antibody technology platform, Harbour Mice®, generates fully human monoclonal antibodies in both the conventional two heavy and two light chain (H2L2) format and the heavy chain-only (HCAb) format. Building upon HCAb antibodies, the HCAb-based immune cell engagers (HBICE®) bispecific antibody technology enables tumor-killing effects that traditional combination therapies cannot achieve. The HCAb-based Antibody Plus technology (HCAb PLUS™) provides comprehensive modality solutions for the development of innovative multi-specific medicines in different disease areas. Additionally, building upon the Harbour Mice® platform, Harbour BioMed launched its first fully human Generative AI HCAb Model powered by its Hu-mAtrIx™AI platform, accelerating the development of innovative therapies.

By integrating Harbour Mice®, HBICE®, HCAb PLUS™, a single B-cell cloning platform and AI technologies, Harbour BioMed has built a highly efficient and distinctive antibody discovery engine for developing next-generation therapeutic antibodies. 

140+
Partners
380+
Projects
20+
IND/Clinical Stage
Led by over a hundred senior scientists, with R&D centers located across China, the United States, and Europe.
Technology Platforms
Core Underlying Technologies Driving Innovation
Our Harbour Mice® antibody technology platforms are supported by a comprehensive suite of in-house technology tools, including but not limited to single B cell cloning, next-generation sequencing, immunizations, bioinformatics, protein science, yeast/phage/mammalian display libraries, antibody engineering and artificial intelligence, effectively accelerating the development of innovative biotherapeutics.
  • Harbour Mice<sup>®</sup>
    Harbour Mice®

    Our proprietary fully human transgenic mouse platform generates fully human, affinity-matured classical antibodies (H2L2) and heavy chain-only antibodies (HCAb) with excellent developability.

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  • Single-Cell Technology Platform
    Single-Cell Technology Platform

    Utilizing state-of-the-art Beacon optofluidic technology, we have established a full process for single B cell cloning, significantly increasing the efficiency and productivity of antibody drug discovery.

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  • HBICE<sup>®</sup>
    HBICE®

    Based on the heavy chain-only antibodies generated from the HCAb Harbour Mice® platform, we have established the proprietary HBICE® (HCAb-Based Immune Cell Engagers) platform to rapidly develop bispecific/multi-specific antibodies that redirect immune cells to the tumor microenvironment (TME) for tumor eradication.

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Fully human Generative AI HCAb Model
AI-Empowered Fully Human Antibody Discovery

Built on the Harbour Mice® platform, Harbour BioMed launched the world' s first fully human Generative AI HCAb (Heavy Chain-Only Antibody) Model, accelerating the development of innovative therapies.

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AI Design
AI Design
Intelligent Screening
Intelligent Screening
Wet-Lab Validation
Wet-Lab Validation
Partnership
Global Strategic Collaborations and Ecosystem
External collaboration has always been a core component of Harbour BioMed's strategic development. We have R&D centers in the United States, Europe, and China, fully leveraging the innovation advantages of each region to serve patients globally.
Technology Service

High quality technology support through fee for service and FTE

Technology License

Access to world's leading fully human Harbour Mice® platform

Asset License

Novel pipelines with best-in-class potential for global innovation

Co-development

Leverage synergistic advantages to collaboratively develop breakthrough therapies

Strategic Collaboration

Comprehensive long-term collaboration utilizing Harbour's proprietary platform to develop next-generation therapeutics

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Technology Service

High quality technology support through fee for service and FTE

Technology License

Access to world's leading fully human Harbour Mice® platform

Asset License

Novel pipelines with best-in-class potential for global innovation

Co-development

Leverage synergistic advantages to collaboratively develop breakthrough therapies

Strategic Collaboration

Comprehensive long-term collaboration utilizing Harbour's proprietary platform to develop next-generation therapeutics

01/05