Harbour BioMed (HKEX: 02142) is a global biopharmaceutical company committed to the discovery and development of novel antibody therapeutics in immunology, oncology and other areas. The Company is building a robust portfolio and differentiated pipeline through internal R&D capability, strategic global collaborations in co-discovery and co-development, and selective acquisitions.
Our proprietary antibody technology platform, Harbour Mice®, generates fully human monoclonal antibodies in both the conventional two heavy and two light chain (H2L2) format and the heavy chain-only (HCAb) format. Building upon HCAb antibodies, the HCAb-based immune cell engagers (HBICE®) bispecific antibody technology enables tumor-killing effects that traditional combination therapies cannot achieve. The HCAb-based Antibody Plus technology (HCAb PLUSTM) provides comprehensive modality solutions for the development of innovative multi-specific medicines in different disease areas. Additionally, building upon the Harbour Mice® platform, Harbour BioMed launched its first fully human Generative AI HCAb Model powered by its Hu-mAtrIxTM AI platform, accelerating the development of innovative therapies.
By integrating Harbour Mice®, HBICE®, HCAb PLUSTM, a single B-cell cloning platform and AI technologies, Harbour BioMed has built a highly efficient and distinctive antibody discovery engine for developing next-generation therapeutic antibodies.
Our proprietary antibody technology platforms Harbour Mice® generate fully human antibodies. The platforms have broad potential for generating both conventional as well as the Next-Gen biologics that are fully human, affinity matured with excellent solubility and developability.
Batoclimab HBM9161
FcRn
Myasthenia Gravis
Greater China
(Out-Licensed)
HBM9378
TSLP
Asthma
COPD*
Greater China
(Ex-GC: NewCo)
Greater China
(Ex-GC: NewCo)
HBM7575
TSLP×
Undisclosed
Inflammatory Diseases
Global
HBM2001
TL1A×IL23p19
IBD
Global
J9003
Undisclosed
(mAb)
IBD
Global
R1065
APRIL
IgAN
Global
OX40L Family
OX40L×
Undisclosed
Dermatosis
Global
HBM7020
BCMA×CD3
Autoimmune Diseases
Global
(Out-Licensed)
R2006
CD19×CD3
Autoimmune Diseases
Global
R7027
Undisclosed
(bsAb)
Autoimmune Diseases
Global
Porustobart HBM4003
CTLA-4
Melanoma
CRC*
HCC*
NEN*
Greater China
(Ex-GC: NewCo)
Greater China
(Ex-GC: NewCo)
Greater China
(Ex-GC: NewCo)
Greater China
(Ex-GC: NewCo)
HBM1020
B7H7/HHLA2
Solid Tumors
Global
HBM7022
CLDN18.2×CD3
Solid Tumors
Global
(Out-Licensed)
HBM7008
B7H4×4-1BB
NSCLC
Global
HBM9027
PD-L1×CD40
Pancreatic Cancer
Global
HBM7004
B7H4×CD3
NSCLC
Global
HBM9033
MSLN
(ADC)
Solid Tumors
Global
(Out-Licensed)
LET003
Undisclosed
(mAb)
Obesity
Global
LET001
Undisclosed
(LYTAC)
Obesity
Global
PD1 / Chemo
Breakthrough Therapy Designation
* CRC = Colorectal Cancer
* HCC = Hepatocellular Carcinoma
* NEN = Neuroendocrine Neoplasm
* COPD = Chronic Obstructive Pulmonary Disease
Partnerships are integral to Harbour BioMed's strategy to build a fully integrated biopharmaceutical company. Harbour BioMed has built up global R&D centers within USA, Europe and China.
Company Overview
Harbour Mice
Pipeline
Partnership Models
Newsroom