Technology
Platforms
Passion for Leading Technology Advancement Towards Transformative Solutions
Our Harbour Mice® antibody technology platforms are supported by a comprehensive suite of in-house technology tools, including but not limited to single B cell cloning, next-generation sequencing, immunizations, bioinformatics, protein science, yeast/phage/mammalian display libraries, antibody engineering and artificial intelligence.
Moreover, our HBICE® bispecific technology enables us to generate flexible formats to accommodate different mechanisms of action. Our mammalian direct cloning platform allows for highly efficient bispecific antibody screening, surpassing traditional methods.
We hold exclusive global rights to use and develop our Harbour antibody platforms, which are protected by a robust portfolio of global patents. This intellectual property position enables us to maximize the platform’s value in addressing unmet medical needs worldwide.

These achievements demonstrate our discovery team’s expertise and technical prowess in translating target biology into points of innovation and differentiation. Driven by an experienced group of over 100 scientists with extensive research and drug development experience, our operations in the United States, China, and the Netherlands are advancing our mission:
To Be the Leading Company Driving Global Innovation of Next-Generation Antibody Therapeutics.

Harbour Mice®
Transgenic mice have emerged as powerful tools for use in biologic drug discovery based on their unique potential in producing fully human antibodies. The platforms have broad potential for generating both conventional antibody therapeutics as well as the Next-Gen biologics that are affinity matured, fully human with excellent solubility and developability.
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Single Cell Technology Platform
The single cell technology has been widely used in biomedical research. We acquired Berkeley lights’ advanced Beacon® Optofluidic technology and established our single cell technology platform currently focusing on single B cell cloning to enhance our fully human antibody discovery capability and single cell analysis for translational cancer research.
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Bispecific Antibodies
Harbour HCAb platform can generate diverse and stable fully human Heavy Chain only Antibodies (HCAbs) and derived human VH single-domain moieties, enabling us to make novel multi-specific and multi-valent antibodies in simplified structures with relatively smaller molecule size and fewer number of polypeptide chains. On top of this, we have established proprietary HBICE® (HCAb Based Immune Cell Engagers) platform to quickly develop multi-specific antibodies which redirect immune cells to the tumor microenvironment (TME) to eradicate tumors.
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