October 12th, 2017

SHANGHAI, China, ROTTERDAM, The Netherlands and CAMBRIDGE, MA

Harbour BioMed announced today that it has licensed its patented H2L2 transgenic mouse platform for generating fully human therapeutic monoclonal antibodies, to Innovent Biologics, Inc., a leading biopharmaceutical company in China.  The license was issued through Harbour BioMed’s wholly owned subsidiary, Harbour Antibodies BV.

Harbour BioMed’s transgenic H2L2 platform enables biotechnology and pharmaceutical companies and academic research labs to accelerate new drug development by generating fully human antibodies. Under the licensing agreement, Innovent Biologics has rights to use the H2L2 platform for multiple projects over a multi-year licensing term. Harbour will receive an upfront payment, fees and milestones as well as royalties based on net sales.  Specific financial details were not disclosed.

“Innovent joins more than 30 companies and academic institutions globally as licensees to our transgenic mouse platforms for antibody discovery,” said Dr. Jingsong Wang, CEO of Harbour BioMed. “The increasing adoption of our platforms reflects their power as rapid and efficient antibody discovery tools and our strong intellectual property position.” Dr. Wang noted that the transgenic mice platform licensing operations at Harbour Antibodies complements Harbour BioMed’s therapeutic discovery and development business.

About Harbour BioMed

 
Harbour BioMed (HKEX: 02142) is a global biopharmaceutical company committed to the discovery, development and commercialization of novel antibody therapeutics focusing on oncology and immunology. The Company is building its robust portfolio and differentiated pipeline through internal R&D capability, collaborations with co-discovery and co-development partners and select acquisitions.

 
The Company’s proprietary antibody technology platforms Harbour Mice^® generate fully human monoclonal antibodies in two heavy and two light chain (H2L2) format, as well as heavy chain only (HCAb) format. Building upon the HCAb antibodies, the HCAb-based immune cell engagers (HBICE^®) are capable of delivering tumor killing effects unachievable by traditional combination therapies. Integrating Harbour Mice^® with single B cell cloning platform, our antibody discovery engine is highly unique and efficient for development of next generation therapeutic antibodies. 

For further information, please refer to www.harbourbiomed.com

About Harbour Mice

A fully owned subsidiary of Harbour BioMed, Harbour Antibodies owns two strains of transgenic mice for generating human therapeutic antibodies: (1) mice that generate antibodies comprised of two heavy chains and two light chains (H2L2) with fully human variable regions; and (2) mice that generate novel “heavy chain only” antibodies (HCAb). The HCAb mice enable the development of antibody fragment-based therapeutics such as nanobodies, bi-specific antibodies and CAR-T with favorable drug-like properties.

For more information, please visit http://harbourantibodies.com.

Contact:

Timothy Miller

Harbour Antibodies

90 Bridge Street, Suite 100 

Newton, MA 02478, USA

timothy.miller@harbourbiomed.com